229 research outputs found

    An Intelligent Interactive Knowledge Model for Decision Support in Real Time Traffic Management

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    This paper proposes the use of advanced knowledge models to support real time decision for management problems as an adequate response to the current needs and technology. The new conditions for human operation created by the telematics technology are discussed and a general architecture using knowledge modelling techniques is proposed. Then, the application of the approach to support real time management of the private traffic in the city of Turin is described

    Occurrence and removal of pharmaceuticals in wastewater treatment plants at the Spanish Mediterranean area of Valencia

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    A survey on the presence of pharmaceuticals in urban wastewater of a Spanish Mediterranean area (Castellon province) was carried out. The scope of the study included a wide variety of pharmaceuticals belonging to different therapeutical classes. For this purpose, 112 samples, including influent and effluent wastewater, from different conventional wastewater treatment plants were collected. Two monitoring programmes were carried out along several seasons. The first was in June 2008 and January 2009, and the second in April and October 2009. During the first monitoring, the occurrence of 20 analytes in 84 urban wastewater samples (influent and effluent) was studied. The selection of these pharmaceuticals was mainly based on consumption. From these, 17 compounds were detected in the samples, with analgesics and anti-inflammatories, cholesterol lowering statin drugs and lipid regulators being the most frequently detected groups. 4-Aminoantipyrine, bezafibrate, diclofenac, gemfibrozil, ketoprofen, naproxen and venlafaxine were the compounds most frequently found. In the highlight of these results, the number of analytes was increased up to around 50. A lot of antibiotic compounds were added to the target list as they were considered “priority pharmaceuticals” due to their more potential hazardous effects in the aquatic environment. Data obtained during the second monitoring programme (spring and autumn) corroborated the results from the first one (summer and winter). Analgesics and anti-inflammatories, lipid regulators together with quinolone and macrolide antibiotics were the most abundant pharmaceuticals. Similar median concentrations were found over the year and seasonal variation was not clearly observed. The removal efficiency of pharmaceuticals in the wastewater treatment plants was roughly evaluated. Our results indicated that elimination of most of the selected compounds occurred during the treatment process of influent wastewater, although it was incomplete

    Horizontal collaboration in freight transport: concepts, benefits and environmental challenges

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    [EN] Since its appearance in the 1990s, horizontal collaboration (HC) practices have revealed themselves as catalyzers for optimizing the distribution of goods in freight transport logistics. After introducing the main concepts related to HC, this paper offers a literature review on the topic and provides a classification of best practices in HC. Then, the paper analyses the main benefits and optimization challenges associated with the use of HC at the strategic, tactical, and operational levels. Emerging trends such as the concept of ` green' or environmentally- friendly HC in freight transport logistics are also introduced. Finally, the paper discusses the need of using hybrid optimization methods, such as simheuristics and learnheuristics, in solving some of the previously identified challenges in real- life scenarios dominated by uncertainty and dynamic conditions.This work has been partially supported by the Spanish Ministry of Economy and Competitiveness & FEDER (TRA2013-48180-C3-P, TRA2015-71883-REDT), The Erasmus+ program (2016-1-ES01-KA108-023465), the Ibero American Program of Science and Technology for Development (CYTED2014-515RT-0489), the CAN Foundation (CAN2014-3758, CAN2015-70473), and the Spanish Ministry of Education (FPU-14/00024).Serrano-Hernandez, A.; Juan, AA.; Faulin, J.; Perez-Bernabeu, E. (2017). Horizontal collaboration in freight transport: concepts, benefits and environmental challenges. SORT. Statistics and Operations Research Transactions. 41(2):393-414. https://doi.org/10.2436/20.8080.02.65S39341441

    A robust protocol for in vivo THz skin measurements

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    This work presents an experimental setup to control the way in which pressure interferes with the repeatability of in vivo THz skin measurements. By integrating a pressure sensor circuit into our THz system, it is possible to identify which measurements were taken within a previously specified pressure range. The live response of the pressure sensor helps to acquire data within the desired pressure leading to greater consistency of data between measurements. Additionally, a protocol is proposed to help achieve repeatable results and to remove the effects of the natural variation of the skin through the course of the day. This technique has been shown to be able to quantify the changes induced in the skin following the application of a moisturising skin product and shows the measured result to be significantly different from natural skin variation. This research therefore prepares the way for further studies on the effectiveness of different skin products using in vivo THz measurements

    Identification of new, very long-chain polyunsaturated fatty acids in fish by gas chromatography coupled to quadrupole/time-of-flight mass spectrometry with atmospheric pressure chemical ionization

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    This is a pre-print of an article published in Analytical and Bioanalytical Chemistry. The final authenticated version is available online at: https://doi.org/10.1007/s00216-020-03062-0The characterization of very long-chain (>C24) polyunsaturated fatty acids (VLC-PUFAs), which are essential in the vision, neural function, and reproduction of vertebrates, is challenging because of the lack of reference standards and their very low concentrations in certain lipid classes. In this research, we have developed a new methodology for VLC-PUFA identification based on gas chromatography coupled to quadrupole/time-of-flight mass spectrometry with an atmospheric pressure chemical ionization source (GC-APCI-QTOF MS). The mass accuracy attainable with the innovative QTOF instrument, together with the soft ionization of the APCI source, provides valuable information on the intact molecule, traditionally lost with electron ionization sources due to the extensive fragmentation suffered. We have identified, for the first time, VLC-PUFAs with chains up to 44 carbons in eyes, brain, and gonads of gilthead sea bream, a commercially important fish in the Mediterranean. The added value of ion mobility-mass spectrometry (IMS), recently developed in combination with GC-QTOF MS, and the contribution of the collisional cross section (CCS) parameter in the characterization of novel VLC-PUFAs (for which reference standards are not available) have been also evaluated. The methodology developed has allowed assessing qualitative differences between farmed and wild fish, and opens new perspectives in a still scarcely known field of research

    Evaluation of hemodialysis vascular access. Perspective from Mexico

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    Chronic kidney disease (CKD) has become a global health problem. In 2019, it was related to 2.53% of general global mortality (2.35-2.66%); in the same year, in Latin America, mortality related to CKD reached 5.25% (4.92-5.49%), with an annual increase of 3.37%, proving increased mortality of 102% between 1990 and 2017. A nephrology specialty in Mexico recently fulfilled its first 50 years. Despite being relatively young, nephrologists are interested in “new” sub-specialties of nephrology and learning novel techniques and problem-solving skills. Our group is the first in our country to focus solely and exclusively on comprehensive VA care and we want to position ourselves as the first Mexican interdisciplinary group focused on vascular access (GIMEXAV)

    Propuesta asignación de posiciones y diseño de picking para la compañía Moldo

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    En este proyecto se busca solucionar problemas relacionados con el inventario de la empresa Moldo la cual se dedica a prestar el servicio de alquiler de carpas para eventos, esta compañía actualmente no realiza un control adecuado en cuanto a la organización de los componentes próximos a alquilar ni tampoco en los que llegan a la bodega. Para evitar que esta situación continúe ocurriendo, se elaborará una distribución de posiciones de los productos que cuenta la bodega de Moldo para así realizar un modelo de picking que reduzca la cantidad de complementos faltantes de los pedidos y los tiempos de alistamiento, despacho y descarga, además de que los pedidos se realicen en el mejor tiempo posible. De este modo, garantizar que los pedidos no tengan faltantes.This project seeks to salve problems related to the inventory ofthe company Moldo which is dedicated to provide the service of renting tents for events. This company currently <loes not perform adequate control in organizing neither the tent components to rent nor in those that arrive at the warehouse. To prevent this situation, a re- distribution of positions of products in the Moldo warehouse will be carried out in order to develop a picking mathematical model that reduces the amount of missing elements in the orders, and times of preparation, dispatch and unloading of such orders. In this way, Moldo can ensure that their orders are fulfilled satisfactorily under opportunity, volumen and quality criteria.Ingeniero (a) IndustrialPregrad

    Use of Porous no Metallic Minerals to Remove Heavy Metals, Precious Metals and Rare Earths, by Cationic Exchange

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    This chapter is related with the preliminary study of some non-metallic minerals to evaluate their cationic exchange capacity, to remove heavy and precious metals, as well as rare earths elements. The minerals and materials used to execute the ion metals removal were bentonite, phosphorite, and diatomite. The chapter shows the physicochemical behavior of all these minerals, which were used to remove the mentioned elements from solutions coming from ore leaching. It was found that in all cases, the removal of heavy and precious metals, as well as rare earths elements reached over 90%. Although, there were minimal differences in efficiency for all minerals used (bentonite, phosphorite, and diatomite), it could be pointed that the phosphorite has the best results going from 99.43% of removal of Gd, to 99.95–100% for the case of Ce, Nd, La, Yb, Eu, Er, Sm, Tb, Ge, Pd, Pt, and Au

    Evaluation of in vivo THz sensing for assessing human skin hydration

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    Terahertz (THz) in vivo reflection imaging can be used to assess the water content of the surface of the skin. This study presents the results of treating 20 subjects with aqueous, anhydrous and water-oil emulsion samples and observing the changes induced in the skin using THz imaging. These regions were also measured with a corneometer, the present gold standard for skin hydration assessment within the cosmetics industry. We find that THz imaging is effective at observing the presence of oil and water on the surface of the skin, these results can be verified with the measurements of capacitance taken by the corneometer. The THz measurements reveal a distinction between the responses of subjects with initially dry or well hydrated skin, this observation is particularly noticeable with the oil-based samples. Additionally, moderate correlation was found between the THz reflected amplitude and capacitance of untreated skin with a correlation coefficient of r = -0.66, suggesting THz imaging has promising potential for assessing skin hydration
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